W.-J. Fang, M.A. Bennett, T.F. Murray and J.V. Aldrich, “An Unexpected Side Reaction Involving the Deletion of an Acetylated N-Methyl-amino Acid from the N-Terminus of Peptides,” Understanding Biology Using Peptides, S.E. Blondelle, Ed., American Peptide Soc., 2005, in press.
A.M. Peck, V. Kumar, T.F. Murray and J.V. Aldrich, “Synthesis and Pharmacological Evaluation of Dual Labeled Delta Opioid Receptor Peptides,” Understanding Biology Using Peptides, S.E. Blondelle, Ed., American Peptide Soc., 2005, in press.
X. Wang, T.F. Murray and J.V. Aldrich, “Synthesis and Pharmacological Evaluation of a New Generation of TIPP-Derived Dual Labeled Ligands for Delta Opioid Receptors,” Understanding Biology Using Peptides, S.E. Blondelle, Ed., American Peptide Soc., 2005, in press.
K. Patkar, X. Yan, T.F. Murray and J.V. Aldrich, “[N-BenzylTyr1, cyclo(D-Asp5,Dap8)]-dynorphin A-(1–11)NH2 Cyclized in the “Address” Domain is a Novel ? -Opioid Receptor Antagonist,” J. Med. Chem.2005, in press.
M.A. Bennett, T.F. Murray, and J.V. Aldrich, “Structure-Activity Relationships of Arodyn, a Novel Acetylated Kappa Opioid Receptor Antagonist,” J. Peptide Res.2005, 65, 322-332.
K.F. Hauser, J.V. Aldrich, K.J. Anderson, G. Bakalkin, M.J. Christie, E.D. Hall, P.E. Knapp, S.W. Scheff, I.N. Singh, B. Vissel, A.S. Woods, T. Yakovleva, and T.S. Shippenberg, “Pathobiology of Dynorphins in Trauma and Disease,” Front. Biosci.2005, 10, 216-235.
J.V. Aldrich, H. Choi, and T.F. Murray, “An Affinity Label for d Opioid Receptors Derived from [D-Ala2]Deltorphin I,”J. Peptide Res.2004, 63, 108-115.
B.S. Vig and J.V. Aldrich, “An Inexpensive, Manually Operated, Solid-Phase, Parallel Synthesizer,” Aldrichchimica Acta2004, 37, 2.
B.S. Vig, T.F. Murray, and J.V. Aldrich, “Synthesis and Opioid Activity of Side-Chain-to-Side-Chain Cyclic Dynorphin A-(1-11) Amide Analogues Cyclized between Positions 2 and 5. 1. Substitution in Position 3,”J. Med. Chem. 2004, 47, 446-455.
M.W. Leighty, T.F. Murray, and J.V. Aldrich, “Structure-Activity Relationships of a Novel Cyclic Dynorphin A Analog with Kappa Opioid Receptor Antagonist Activity,” in Peptide Revolution: Genomics, Proteomics, & Therapeutics, M. Chorev and T.K. Sawyer, Eds., American Peptide Soc., San Diego, 2003, pp 691-692.
B.S. Vig, M.Q. Zheng, T.F. Murray, and J.V. Aldrich, “Effects of the Substitution of Phe4 in the Opioid Peptide [D-Ala8]Dynorphin A-(1-11)NH2,” J. Med. Chem. 2003, 46, 4002-4008.
B.S. Vig, T.F. Murray, and J.V. Aldrich, “Synthesis of Novel Basic Head-to-Side-Chain Cyclic Dynorphin A Analogs: Strategies and Side Reactions,” Biopolymers (Peptide Sci.)2003, 71, 620-637.
H. Choi, T. F. Murray, and J.V. Aldrich, “ Synthesis and Evaluation of Derivatives of Leucine Enkephalin as Potential Affinity Labels for d Opioid Receptors,” Biopolymers (Peptide Sci.)2003, 71, 552-557.
H. Choi, T.F. Murray, and J.V. Aldrich, “Dermorphin-Based Potential Affinity Labels for µ-Opioid Receptors,” J. Peptide Res. 2003, 61, 40-45.
H. Choi, T.F. Murray, and J.V. Aldrich, “Synthesis and Evaluation of Potential Affinity Labels Derived from Endomorphin-2,” J. Peptide Res. 2003, 61, 58-62.
J.V. Aldrich and S.C. Vigil-Cruz, “Narcotic Analgesics,” in Burger's Medicinal Chemistry and Drug Discovery, 6 th Ed., D.J. Abraham, Ed., John Wiley, Inc: New York, 2003, vol. 6, pp 329-481.
V. Kumar and J. V. Aldrich, “A Solid-Phase Synthetic Strategy for Labeled Peptides: Synthesis of a Biotinylated Derivative of the d Opioid Receptor Antagonist TIPP (Tyr-Tic-Phe-Phe-OH),” Org. Lett.2003, 5, 613-616.
B.S. Vig, T.F. Murray, and J.V. Aldrich, “A Novel N-Terminal Cyclic Dynorphin A Analogue cycloN,5[Trp3,Trp4, Glu5]Dynorphin A-(1-11)NH2 that Lacks the Basic N-Terminus,” J. Med. Chem. 2003, 46 1279-1282.
V. Kumar, T.F. Murray, and J.V. Aldrich, "Solid Phase Synthesis and Evaluation of Tyr-Tic-Phe-Phe(p-NHCOCH2Br) ([Phe(p-bromoacetamide)4]TIPP), a Potent Affinity Label for d Opioid Receptors," J. Med. Chem.2002, 45, 3820-3823.
M.A. Bennett, T.F. Murray, and J.V. Aldrich, ”Identification of Arodyn, a Novel Acetylated Dynorphin A-(1-11) Analogue, as a ? Opioid Receptor Antagonist,” J. Med. Chem.2002, 45, 5617-5619.
J.V. Aldrich, Q. Zheng, and T.F. Murray, “Dynorphin A Analogues Containing a Conformationally Constrained Phenylalanine Analogue in Position 4: Reversal of Preferred Stereochemistry for Opioid Receptor Affinity and Discrimination of ? vs. d Receptors,” Chirality2001, 13, 125-129.
Sasiela, M. A. Bennett, T.F. Murray and J.V. Aldrich, "C-Terminal Structure-Activity Relationships for the Novel Opioid Peptide JVA-901 (Venorphin)," Peptides: Wave of the Future, M. Lebl and R.A. Houghten, Eds., American Peptide Soc., 2001, pp. 689-690.
K. Patkar, T.F. Murray and J.V. Aldrich, "Design and Synthesis of [N-benzylTyr 1]Dynorphin A-(1-11) Analogs with C-Terminal Modifications and Evaluation of Their Opioid Activity," Peptides: Wave of the Future, M. Lebl and R.A. Houghten, Eds., American Peptide Soc., 2001, pp. 687-688.
L. Leelasvatanakij and J.V. Aldrich, “Solid Phase Synthetic Strategy for the Preparation of Peptide-Based Affinity Labels: Synthesis of Dynorphin A Analogues,” J. Peptide Res.2000, 56, 80-87.
V. Kumar, T.F. Murray, and J.V. Aldrich, “Extended TIP(P) Analogs As Precursors for Labeled d -Opioid Receptor Ligands,” J. Med. Chem., 2000, 43, 5050-5054.
D.Y. Maeda, F. Berman, T.F. Murray, and J.V. Aldrich, “Synthesis and Evaluation of Isothiocyanate-Containing Derivatives of the d Opioid Receptor Antagonist Tyr-Tic-Phe-Phe (TIPP) as Potential Affinity Labels for d Opioid Receptors,” J. Med. Chem.2000, 43, 5044-5049.
D.Y. Maeda, J.E. Ishmael, T.F. Murray, and J.V. Aldrich, “Synthesis and Evaluation of N,N-Dialkyl Enkephalin-Based Affinity Labels for d Opioid Receptors,” J. Med. Chem.2000, 43, 3941-3948.
