K.A. Patkar, W.E. Highsmith, J.V. Aldrich, "Solid Phase and Solution Synthesis of Nvo cLys(CO(CH2)5NH-NBD)OCH2CN, a Trifunctional Fluorescent Lysine Derivative," Amino Acids. 2009, 36, 203-207.
J.V. Aldrich, V. Kumar, T.F. Murray, W. Guang, J.B. Wang, "Dual Labeled Peptides as Tools to Study Receptors: Nanomolar Affinity Derivatives of TIPP (Tyr-Tic-Phe-Phe) Containing an Affinity Label and Biotin as Probes of Opioid Receptors," Bioconj. Chem. 2009, 20, 201-204.
B. Dattachowdhury, T.F. Murray, J.V. Aldrich, "The Synthesis of DAMGO-Based Potential Affinity Labels with High Mu Opioid Receptor Affinity and the Formation of Cyclic O-Alkyl Thiocarbamates," Adv. Exp. Med. Biol. 2009, 6, 265-266.
S.S. Kulkarni, N.C. Ross, J.P. McLaughlin, J.V. Aldrich, "Synthesis of Cyclic Tetrapeptide CJ 15,208: A Novel Kappa Opioid Receptor Antagonist," Adv. Exp. Med. Biol. 2009, 6, 269-270.
W.-J. Fang, S.S. Kulkarni, T.F. Murray, J.V. Aldrich, "Design and Synthesis of Cyclic Arodyn Analogues by Ring-Closing Metathesis (RCM) for Kappa Opioid Receptor (KOP) Antagonists," Adv. Exp. Med. Biol. 2009, 6, 279-280.
J.V. Aldrich, V. Kumar, B. Dattachowdhury, A.M. Peck, X. Wang, T.F. Murray, "Solid Phase Synthesis and Application of Labeled Peptide Derivatives: Probes of Receptor-Opioid Peptide Interactions," Int. J. Pep. Res. Ther. 2008, 14, 315-321.
L. Charoenchai, H. Wang, J.B. Wang, J.V. Aldrich, "High Affinity Conformationally Constrained Nociceptin/Orphanin FQ (1-13) Amide Analogs," J. Med. Chem. 2008, 51, 4385-4387.
A.N. Carey, K. Borozny, J.V. Aldrich, J.P. McLaughlin, "Reinstatement of Cocaine Place-Conditioning Prevented by the Peptide Kappa-Opioid Receptor Antagonist Arodyn," Eur. J. Pharmacol. 2007, 569, 84-89.
Z. Marinova et al, "Translocation of Dynorphin Neuropeptides Across the Plasma Membrane: A Putative Mechanism of Signal Transmission," J. Biol. Chem. 2005, 280, 26360-26370.
K.A. Patkar, X. Yan, T.F. Murray, J.V. Aldrich, "[N -BenzylTyr1,cyclo(D-Asp5,Dap8)]-dynorphin A-(1-11)NH2 Cyclized in the 'Address' Domain is a Novel -Opioid Receptor Antagonist," J. Med. Chem. 2005, 48, 4500-4503.
M.A. Bennett, T.F. Murray, J.V. Aldrich, "Structure-Activity Relationships of Arodyn, a Novel Acetylated Kapp Opioid Receptor Antagonist," J. Pep. Res. 2005, 65, 322-332.
K.F. Hauser, J.V. Aldrich, K.J. Anderson, G. Bakalkin, M.J. Christie, E.D. Hall, P.E. Knapp, S.W. Scheff, I.N. Singh, B. Vissel, A.S. Woods, T. Yakovleva, T.S. Shippenberg, "Pathobiology of Dynorphins in Trauma and Disease," Front. Biosci. 2005, 10, 216-235.
J.V. Aldrich, H. Choi, and T.F. Murray, “An Affinity Label for d Opioid Receptors Derived from [D-Ala2]Deltorphin I,”J. Peptide Res.2004, 63, 108-115.
B.S. Vig, T.F. Murray, and J.V. Aldrich, “Synthesis and Opioid Activity of Side-Chain-to-Side-Chain Cyclic Dynorphin A-(1-11) Amide Analogues Cyclized between Positions 2 and 5. 1. Substitution in Position 3,”J. Med. Chem. 2004, 47, 446-455.
M.W. Leighty, T.F. Murray, and J.V. Aldrich, “Structure-Activity Relationships of a Novel Cyclic Dynorphin A Analog with Kappa Opioid Receptor Antagonist Activity,” in Peptide Revolution: Genomics, Proteomics, & Therapeutics, M. Chorev and T.K. Sawyer, Eds., American Peptide Soc., San Diego, 2003, pp 691-692.
B.S. Vig, M.Q. Zheng, T.F. Murray, and J.V. Aldrich, “Effects of the Substitution of Phe4 in the Opioid Peptide [D-Ala8]Dynorphin A-(1-11)NH2,” J. Med. Chem. 2003, 46, 4002-4008.
B.S. Vig, T.F. Murray, and J.V. Aldrich, “Synthesis of Novel Basic Head-to-Side-Chain Cyclic Dynorphin A Analogs: Strategies and Side Reactions,” Biopolymers (Peptide Sci.)2003, 71, 620-637.
H. Choi, T. F. Murray, and J.V. Aldrich, “ Synthesis and Evaluation of Derivatives of Leucine Enkephalin as Potential Affinity Labels for d Opioid Receptors,” Biopolymers (Peptide Sci.)2003, 71, 552-557.
H. Choi, T.F. Murray, and J.V. Aldrich, “Dermorphin-Based Potential Affinity Labels for µ-Opioid Receptors,” J. Peptide Res. 2003, 61, 40-45.
H. Choi, T.F. Murray, and J.V. Aldrich, “Synthesis and Evaluation of Potential Affinity Labels Derived from Endomorphin-2,” J. Peptide Res. 2003, 61, 58-62.
J.V. Aldrich and S.C. Vigil-Cruz, “Narcotic Analgesics,” in Burger's Medicinal Chemistry and Drug Discovery, 6 th Ed., D.J. Abraham, Ed., John Wiley, Inc: New York, 2003, vol. 6, pp 329-481.
V. Kumar and J. V. Aldrich, “A Solid-Phase Synthetic Strategy for Labeled Peptides: Synthesis of a Biotinylated Derivative of the d Opioid Receptor Antagonist TIPP (Tyr-Tic-Phe-Phe-OH),” Org. Lett.2003, 5, 613-616.
B.S. Vig, T.F. Murray, and J.V. Aldrich, “A Novel N-Terminal Cyclic Dynorphin A Analogue cycloN,5[Trp3,Trp4, Glu5]Dynorphin A-(1-11)NH2 that Lacks the Basic N-Terminus,” J. Med. Chem. 2003, 46 1279-1282.
V. Kumar, T.F. Murray, and J.V. Aldrich, "Solid Phase Synthesis and Evaluation of Tyr-Tic-Phe-Phe(p-NHCOCH2Br) ([Phe(p-bromoacetamide)4]TIPP), a Potent Affinity Label for d Opioid Receptors," J. Med. Chem.2002, 45, 3820-3823.
M.A. Bennett, T.F. Murray, and J.V. Aldrich, ”Identification of Arodyn, a Novel Acetylated Dynorphin A-(1-11) Analogue, as a ? Opioid Receptor Antagonist,” J. Med. Chem.2002, 45, 5617-5619.
J.V. Aldrich, Q. Zheng, and T.F. Murray, “Dynorphin A Analogues Containing a Conformationally Constrained Phenylalanine Analogue in Position 4: Reversal of Preferred Stereochemistry for Opioid Receptor Affinity and Discrimination of ? vs. d Receptors,” Chirality2001, 13, 125-129.
Sasiela, M. A. Bennett, T.F. Murray and J.V. Aldrich, "C-Terminal Structure-Activity Relationships for the Novel Opioid Peptide JVA-901 (Venorphin)," Peptides: Wave of the Future, M. Lebl and R.A. Houghten, Eds., American Peptide Soc., 2001, pp. 689-690.
K. Patkar, T.F. Murray and J.V. Aldrich, "Design and Synthesis of [N-benzylTyr 1]Dynorphin A-(1-11) Analogs with C-Terminal Modifications and Evaluation of Their Opioid Activity," Peptides: Wave of the Future, M. Lebl and R.A. Houghten, Eds., American Peptide Soc., 2001, pp. 687-688.
L. Leelasvatanakij and J.V. Aldrich, “Solid Phase Synthetic Strategy for the Preparation of Peptide-Based Affinity Labels: Synthesis of Dynorphin A Analogues,” J. Peptide Res.2000, 56, 80-87.
V. Kumar, T.F. Murray, and J.V. Aldrich, “Extended TIP(P) Analogs As Precursors for Labeled d -Opioid Receptor Ligands,” J. Med. Chem., 2000, 43, 5050-5054.
D.Y. Maeda, F. Berman, T.F. Murray, and J.V. Aldrich, “Synthesis and Evaluation of Isothiocyanate-Containing Derivatives of the d Opioid Receptor Antagonist Tyr-Tic-Phe-Phe (TIPP) as Potential Affinity Labels for d Opioid Receptors,” J. Med. Chem.2000, 43, 5044-5049.
D.Y. Maeda, J.E. Ishmael, T.F. Murray, and J.V. Aldrich, “Synthesis and Evaluation of N,N-Dialkyl Enkephalin-Based Affinity Labels for d Opioid Receptors,” J. Med. Chem.2000, 43, 3941-3948.
