Department of Medicinal Chemistry
Jeff Aubé
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Aubé Research Group News
Best wishes to Erin Hirt in her new position as Postdoctoral Scientist in the Department of Drug Discovery at Research Triangle Institute International in Research Triangle Park.
Along with several other inventors, Yuguang Wang has received a 2008 Thomas Alva Edison Patent Award in Emerging Technology, recognizing the team’s innovations in Thrombin Receptor Antagonists. These annual awards are given by the Research & Development Council of New Jersey. Congratulations, Yuguang!
Congratulations to Mehmet Tanol, Ph.D., Research Associate at the KU Biotechnology Innovation & Optimization Center, who recently achieved U.S. citizenship along with his wife Oznur!
Best wishes to Timothy Ribelin in his new position as Associate Scientist in the Department of Medicinal Chemistry - Infectious Diseases at GlaxoSmithKline in Philadelphia!
Congratulations to Michael Wolfe on his recent promotion to Professor at Harvard Medical School and Brigham and Women's Hospital’s Center for Neurologic Diseases!
Research Projects
Our laboratory focuses on the development of new synthetic techniques, total synthesis, and the study of peptidomimetics. In addition, the group collaborates with scientists in related areas of medicinal chemistry and drug delivery. The following links will bring you to brief descriptions of our various projects and lead references. For a more complete list of papers published in any given area, please consult the comprehensive bibliography page.
The Azido-Schmidt Family of Reactions
Total Synthesis of Alkaloids
Parallel Synthesis
Peptide Mimicry
Bizarro Mechanism Problems We Have Grown to Know and Love
Oxaziridine Chemistry
Transport Across Biological Membranes
Enzyme Inhibitors
The Aube Research Group, Summer 2009
Standing (left to right): Angelica Meyer, Jennifer Treece, Denise Simpson, Thomas Coombs, Gurpreet Singh, Jeff Aubé, Kevin Frankowski, Partha Ghosh, Thomas Painter
Seated (left to right): Hashim Motiwala, Erik Fenster, Michal Szostak, Brooks Maki, Paul Thornton, Ruzhang Liu, Matt Meinig

Jeff with Greg Milligan, discoverer of the intramolecular Schmidt reaction, taking a break for lunch at the Chicago ACS meeting in March 2007.
Study and PhD fellowships with the: International Quality Network for Medicinal Chemistry
Previous Group Members
Downloads, Links and Schedules



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