Research PublicationsBooks & Review ArticlesMiscellaneous Publications
Research Publications
1. "Deprotonations, Conjugate Additions, and Enolate Trapping of Oxime Ethers and Dimethylhydrazones Using KDA. The Effect of Diisopropylamine on Enolate Trapping." R.E. Gawley, E.J. Termine, and J. Aubé, Tetrahedron Letters, 1980, 21, 3115-3119.
2. "Regiochemistry in the Intramolecular Cycloadditions of Substituted 5-Alkenyl and 6-Alkenyl Nitrones." S.W. Baldwin, J.D. Wilson, and J. Aubé, Journal of Organic Chemistry, 1985, 50, 4432-4439.
3. "Stereospecific Synthesis and Ring Closure of a Racemic Actinospectose Equivalent: A Concise Route to the Spectinomycin Series." Samuel Danishefsky, Jeffrey Aubé, and Mark Bednarski, Journal of the American Chemical Society, 1986, 108, 4145-4149.
4. "Asymmetric Synthesis with Chiral Hydroxylamines. Synthesis of Optically Pure 4-Substituted Azetidinones." S.W. Baldwin and J. Aubé, Tetrahedron Letters, 1987, 28, 179-182.
5. "Selectivity in an Asymmetric Nitrogen Insertion Process." Jeffrey Aubé, Paul M. Burgett, and Yuguang Wang, Tetrahedron Letters, 1988, 29, 151-154.
6. "An Enantioselective Synthesis of (–)-Alloyohimbane." Jeffrey Aubé, Tetrahedron Letters, 1988, 29, 4509-4512.
7. "Diastereotopic Group Selectivity in the Deprotonation of (?-Arene)Cr(CO)3 Complexes." Joseph A. Heppert, M. Elizabeth Thomas-Miller, Michael L. Milligan, David Vander Velde, and Jeffrey Aubé, Organometallics, 1988, 7, 2581-2584.
8. "Unusual Spectroscopic and Conformational Properties of Some Spirocyclic Oxaziridines." Jeffrey Aubé and Yuguang Wang, Tetrahedron Letters, 1988, 29, 6407-6408.
9. "A Convenient Preparation of 2-[15N]-Amino-4,6-dimethoxypyrimidine." Thomas K. Spencer, Gunda I. Georg, and Jeffrey Aubé, Journal of Radiolabelled Compounds and Radiopharmaceuticals, 1990, 28, 433-436.
10. "Diastereotopic Group Selective Reactions at -Arene Chromium Derivatives: Deprotonation and Nucleophilic Addition Reactions of Substrates Bearing Benzylic Chiral Centers." Joseph A. Heppert, Jeffrey Aubé, M. Elizabeth Thomas-Miller, Michael L. Milligan, and Fusao Takusagawa, Organometallics, 1990, 9, 727-739.
11. "Synthetic Aspects of an Asymmetric Nitrogen Insertion Process: Preparation of Chiral, Non-Racemic Caprolactams and Valerolactams. Total Synthesis of (–)-Alloyohimbane." Jeffrey Aubé, Yuguang Wang, Marlys Hammond, Mehmet Tanol, Fusao Takusagawa, and David Vander Velde, Journal of the American Chemical Society, 1990, 112, 4879-4891.
12. "Directed Regiochemical Control in the Ring Expansion Reactions of a Substituted Trans-Decalone." Jeffrey Aubé and Marlys Hammond, Tetrahedron Letters, 1990, 31, 2963-2966. Correction: Ibid. 1992, 33, 1246.
13. "Syntheses and Reactions of Spirocyclic Oxaziridines Derived from Unsymmetrical Ketones." Jeffrey Aubé, Marlys Hammond, Elyse Gherardini, and Fusao Takusagawa, Journal of Organic Chemistry, 1991, 56, 499-508. Correction: J. Org. Chem. 1991, 56, 4086.
14. "Oxaziridine-Mediated Ring Expansions of Substituted Cyclobutanones: Synthesis of (–)-?-Amino-ß-hydroxybutyric Acid (GABOB)." Jeffrey Aubé, Yuguang Wang, Shomir Ghosh, and Kendra L. Langhans, Synthetic Communications, 1991, 21, 693-701.
15. "Diastereoselectivity in the Intramolecular Cycloaddition Reactions of Nitrones Derived from 5-Alkenals and Chiral Hydroxylamines." S.W. Baldwin, R.B. McFadyen, J. Aubé, and J.D. Wilson, Tetrahedron Letters, 1991, 32, 4431-4434.
16. "Studies Directed at the Synthesis of Optically Active Pretazettine via Intramolecular Nitrone/Alkene Cycloaddition Reactions." S.W. Baldwin, J. Aubé, and A.T. McPhail, Journal of Organic Chemistry, 1991, 56, 6546-6550.
17. "Intramolecular Schmidt Reaction of Alkyl Azides." Jeffrey Aubé and Gregory L. Milligan, Journal of the American Chemical Society, 1991, 113, 8965-8966.
18. "TiCl4-Mediated Reactions of Alkyl Azides and Cyclic Ketones." Jeffrey Aubé, Gregory L. Milligan, and Craig J. Mossman, Journal of Organic Chemistry, 1992, 57, 1635-1637.
19. "Asymmetric Deprotonation and Complexation Reactions Mediated by Chiral Ketals as a Route to Substituted (?6-Arene)Cr(CO)3 Complexes." Jeffrey Aubé, Joseph A. Heppert, Michael L. Milligan, Mary Jane Smith, and Paul Zenk, Journal of Organic Chemistry, 1992, 57, 3563-3570.
20. "New Copper(I)-Catalyzed Reactions of Oxaziridines: Stereochemical Control of Product Distribution." Jeffrey Aubé, Xin Peng, Yuguang Wang, and Fusao Takusagawa, Journal of the American Chemical Society, 1992, 114, 5466-5467.
21. "A Divergent Route to Lactam-Based Dipeptidyl Building Blocks." Jeffrey Aubé and Michael S. Wolfe, Bioorganic and Medicinal Chemistry Letters, 1992, 2, 925-928.
22. "Synthesis of Enantiopure N-tert-Butoxycarbonyl-2-aminocycloalkanones." Jeffrey Aubé, Michael S. Wolfe, Rhonda K. Yantiss, Scott M. Cook, and Fusao Takusagawa, Synthetic Communications, 1992, 22, 3003-3012.
23. "(2S, 3S, 5S)- and (2S, 3S, 5R )-5-Carboxaldehyde-2,3-diphenyl-1,4-dioxane as Surrogates for Optically Pure 2,3-O-Isopropylideneglyceraldehyde in Asymmetric Synthesis." Jeffrey Aubé, Craig J. Mossman, and Susan Dickey, Tetrahedron, 1992, 48, 9819-9826.
24. "The Internal Quaternary Ammonium Receptor Site of Shaker Potassium Channels." Kathleen L. Choi, Craig Mossman, Jeffrey Aubé, and Gary Yellen, Neuron, 1993, 10, 533-541.
25. "Application of the Intramolecular Schmidt Reaction to the Asymmetric Synthesis of (–)-Indolizidine 209B from Pulegone." Jeffrey Aubé, Pat S. Rafferty, and Gregory L. Milligan, Heterocycles, 1993, 35, 1141-1147.
26. "The First Synthesis of a C-9 Carbonyl Modified Baccatin III Derivative and Its Conversion to Novel Taxol® and Taxotere® Analogues." Apurba Datta, Jeffrey Aubé, Gunda I. Georg, Lester A. Mitscher, and Lalith R. Jayasinghe, Bioorganic and Medicinal Chemistry Letters, 1994, 4, 1831-1834.
27. "Symmetry-Driven Synthesis of Indole Alkaloids: Asymmetric Total Syntheses of (+)-Yohimbine, (–)-Yohimbone, (–)-Yohimbane, and (+)-Alloyohimbane." Jeffrey Aubé, Shomir Ghosh, and Mehmet Tanol, Journal of the American Chemical Society, 1994, 116, 9009-9018.
28. "Synthesis of cis-d-Phenylmethyl-D-Proline Using a Nitrogen-Centered Radical Derived from a Chiral Oxaziridine." Jeffrey Aubé, Belgin Gülgeze, and Xin Peng, Bioorganic and Medicinal Letters, 1994, 4, 2461-2464.
29. "Synthesis of 13-epi-Taxol via a Transannular Delivery of a Borohydride Reagent." Michael Z. Hoemann, David Vander Velde, Jeffrey Aubé, Gunda I. Georg, and Lalith R. Jayasinghe, Journal of Organic Chemistry, 1995, 60, 2918-2921.
30. "Structural Analysis of ß-Turn Mimics Containing a Substituted 6-Aminocaproic Acid Linker." Osamu Kitagawa, David Vander Velde, Dinah Dutta, Martha Morton, Fusao Takusagawa, and Jeffrey Aubé, Journal of the American Chemical Society, 1995, 117, 5169-5178.
31. "An Efficient Nitrogen Ring-Expansion Process Facilitated by in situ Tethering of an Alkyl Azide to Ketones. An Asymmetric Schmidt Reaction." Vijaya Gracias, Gregory L. Milligan, and Jeffrey Aubé, Journal of the American Chemical Society, 1995, 117, 8047-8048.
32. "Novel Cytotoxic 3'-(tert-Butyl) 3'-Dephenyl Analogs of Paclitaxel and Docetaxel." Syed M. Ali, Michael Z. Hoemann, Jeffrey Aubé, Lester A. Mitscher, Gunda I. Georg, Randy McCall, and Lalith R. Jayasinghe, Journal of Medicinal Chemistry, 1995, 38, 3821-3828.
33. "Intramolecular Schmidt Reactions of Alkyl Azides with Ketones: Scope and Stereochemical Studies." Gregory L. Milligan, Craig J. Mossman, and Jeffrey Aubé, Journal of the American Chemical Society, 1995, 117, 10449-10459.
34. "Conformational Analysis and Structural Elucidation of Spirocyclic Oxaziridines Using NMR, Crystallography, and Molecular Modeling." Yoshinosuke Usuki, Yuguang Wang, and Jeffrey Aubé, Journal of Organic Chemistry, 1995, 60, 8028-8035.
35. "Synthesis of Functionalized N-Alkyl Heterocycles from Ketones by a Sequential Ring Expansion/Nucleophilic Addition Sequence." Vijaya Gracias, Gregory L. Milligan, and Jeffrey Aubé, Journal of Organic Chemistry, 1996, 61, 10-11.
36. "Total Synthesis of Curacin A." Michael Z. Hoemann, Konstantinos A. Agrios, and Jeffrey Aubé, Tetrahedron Letters, 1996, 37, 953-956.
37. "Toward the Synthesis of Sparteine: Intramolecular Schmidt Reactions on a Norbornanone Platform." John A. Wendt and Jeffrey Aubé, Tetrahedron Letters, 1996, 37, 1531-1534.
38. "Intramolecular Schmidt Reactions of Alkyl Azides with Ketals and Enol Ethers." Craig J. Mossman and Jeffrey Aubé, Tetrahedron, 1996, 52, 3403-3408.
39. "One-Step Conversion of Aldehydes to Oxazolines and 5,6-Dihydro-4H-1,3-oxazines Using 1,2- and 1,3-Azido Alcohols." Jennifer G. Badiang and Jeffrey Aubé, Journal of Organic Chemistry, 1996, 61, 2484-2487.
40. "Butitaxel Analogues: Synthesis and Structure–Activity Relationships." Syed M. Ali, Michael Z. Hoemann, Jeffrey Aubé, Gunda I. Georg, Lester A. Mitscher, and Lalith R. Jayasinghe, Journal of Medicinal Chemistry, 1997, 40, 236-241.
41. "Stereoselective Synthesis of Freidinger Lactams Using Oxaziridines Derived from Amino Acids." Michael S. Wolfe, Dinah Dutta, and Jeffrey Aubé, Journal of Organic Chemistry, 1997, 62, 654-663.
42. "Total Synthesis of (+)-Curacin A, a Marine Cytotoxic Agent." Michael Z. Hoemann, Konstantinos A. Agrios, and Jeffrey Aubé, Tetrahedron, 1997, 53, 11087-11098. (Special Issue in Honor of Professor Samuel Danishefsky.)
43. "Effect of Stereochemistry on the Transport of Aca-Linked ß-Turn Peptidomimetics Across a Human Intestinal Cell Line." Kiyoshi Tamura, Konstantinos A. Agrios, David Vander Velde, Jeffrey Aubé, and Ronald T. Borchardt, Bioorganic and Medicinal Chemistry, 1997, 5, 1859-1866.
44. "Ring Expansion by in situ Tethering of Hydroxy Azides to Ketones: The Boyer Reaction." Vijaya Gracias, Kristine E. Frank, Gregory L. Milligan, and Jeffrey Aubé, Tetrahedron, 1997, 53, 16241-16252. (Symposium-in-Print on New Synthetic Methods V)
45. "Syntheses and Evaluation of Peptidyl Michael Acceptors That Inactivate Human Rhinovirus 3C Protease and Inhibit Virus Replication." Jian-she Kong, Shankar Venkatraman, Kelly Furness, Sanjay Nimkar, Timothy A. Shepard, Q. May Wang, Jeffrey Aubé, and Robert P. Hanzlik, Journal of Medicinal Chemistry, 1998, 41, 2579-2587.
46. “Lewis Acid-mediated Cyclizations of (2'-Amino-N'-tert-butoxycarbonyl-benzylidene)-3-alkenylamines.” Kristine E. Frank and Jeffrey Aubé, Tetrahedron Letters, 1998, 39, 7239-7242.
47. “Mannich Reactions Using Benzyl Azide as a Latent N-(Phenylamino)methylating Agent.” Klaas Schildknegt, Konstantinos A. Agrios, and Jeffrey Aubé, Tetrahedron Letters, 1998, 39, 7687-7690.
48. "Reactions of Oxazolinium and Dihydrooxazinium Salts Prepared by an Azide Insertion Sequence: pH Control of Product Distribution.” Jennifer E. Forsee, Brent T. Smith, Kristine E. Frank, and Jeffrey Aubé, Synlett, 1998, 1258-1260.
49. “Design, Synthesis and Evaluation of Azapeptides as Substrates and Inhibitors for Human Rhinovirus 3C Protease.” Shankar Venkatraman, Jian-she Kong, Sanjay Nimkar, Q. May Wang, Jeffrey Aubé, and Robert P. Hanzlik, Bioorganic and Medicinal Chemistry Letters, 1999, 9, 577-580.
50. “Hydrolysis of Iminium Ethers Derived from the Reaction of Ketones with Hydroxy Azides: Synthesis of Macrocyclic Lactams and Lactones.” Jennifer E. Forsee and Jeffrey Aubé, Journal of Organic Chemistry, 1999, 64, 4381-4385.
51. “1,7-Asymmetric Induction in a Nitrogen Ring Expansion Process Facilitated by in situ Tethering.” Kelly Furness and Jeffrey Aubé, Organic Letters, 1999, 1, 495-497.
52. “Cyclizations of Substituted Benzylidene-3-alkenylamines: Synthesis of the Tricyclic Core of the Martinellines.” Kristine E. Frank and Jeffrey Aubé, Journal of Organic Chemistry, 2000, 65, 655-666.
53. "Regiocontrol in an Intramolecular Schmidt Reaction: Total Synthesis of (+)-Aspidospermidine." Rajesh Iyengar, Klaas Schildknegt, and Jeffrey Aubé, Organic Letters, 2000, 2, 1625-1627.
54. "Synthesis and Conformation of Gly-Gly Dipeptides Constrained with Phenylalanine-like Aminocaproic Acid Linkers." Mary MacDonald, David Vander Velde, and Jeffrey Aubé, Organic Letters, 2000, 2, 1653-1655.
55. "Regiochemistry of the Ring Expansion Reactions of Hydroxy Azides with Cyclic Ketones." Brenton T. Smith, Vijaya Gracias, and Jeffrey Aubé, Journal of Organic Chemistry, 2000, 65, 3771-3774.
56. "Reactivity Toward Deamidation of Asparagine Residues in ß-Turn Structures." M. Xie, J. Aubé, R.T. Borchardt, M. Morton, E.M. Topp, D. Vander Velde, and R.L. Schowen, Journal of Peptide Research, 2000, 56, 165-171.
57. "Synthesis of a-Amino- a'-diazomethyl Ketones via Ring Opening of Substituted Cyclopropanones with Alkyl Azides. A Facile Route to N-Substituted 3-Azetidinones." Pankaj Desai and Jeffrey Aubé, Organic Letters, 2000, 2, 1657-1659.
58. "Reactions of Alkyl Azides and Ketones as Mediated by Lewis Acids: Schmidt and Mannich Reactions Using Azide Precursors." Pankaj Desai, Klaas Schildknegt, Konstantinos A. Agrios, Craig Mossman, Gregory L. Milligan, and Jeffrey Aubé, Journal of the American Chemical Society, 2000, 122, 7226-7232..
59. "Stereochemistry of the Oxidation of Imines Derived from Substituted Cyclohexanones: Axial vs. Equatorial Attack and Evidence for Delivery by an Adjacent Hydroxyl Group." Yuguang Wang, Samuel Chackalamannil, and Jeffrey Aubé, Journal of Organic Chemistry, 2000, 65, 5120-5126.
60. "A Functional Assay for Quantitation of the Apparent Affinities of Ligands of P-Glycoprotein in Caco-2 Cells." Jinnian Gao, Osamu Murase, Richard L. Schowen, Jeffrey Aubé, and Ronald Borchardt, Pharmaceutical Research, 2001, 18, 171-177.
61. "Transport Characteristics of Peptides and Peptidomimetics: I. N-Methylated Peptides as Substrates for the Oligopeptide Transporter and P-Glycoprotein in the Intestinal Mucosa." Jinnian Gao, Masao Sudoh, Jeffrey Aubé, and Ronald T. Borchardt, Journal of Peptide Research, 2001, 57, 316-329.
62. "Transport Characteristics of Peptides and Peptidomimetics: II. Hydroxyethylamine Bioisostere-Containing Peptidomimetics as Substrates for the Oligopeptide Transporter and P-Glycoprotein in the Intestinal Mucosa." Jinnian Gao, Stephanie L. Winslow, David Vander Velde, Jeffrey Aubé, and Ronald T. Borchardt, Journal of Peptide Research, 2001, 57, 361-373..
63. "Intramolecular Reactions of Benzylic Azides with Ketones: Competition Between Schmidt and Mannich Pathways." Aaron Wrobleski and Jeffrey Aubé, Journal of Organic Chemistry, 2001, 66, 886-889.
64. "Effect of Progressive Benzyl Substitution on the Conformations of Aminocaproic Acid-Cyclized Dipeptides." Mary MacDonald, David Vander Velde, and Jeffrey Aubé, Journal of Organic Chemistry, 2001, 66, 2636-2642.
65. "A Combined Intramolecular Diels-Alder/Intramolecular Schmidt Reaction: Formal Synthesis of (±)-Stenine." Jennifer E. Golden and Jeffrey Aubé, Angewandte Chemie, International Edition, 2002, 41, 4316-4318.
66. "First Asymmetric Total Synthesis of (+)-Sparteine." Brenton T. Smith, John A. Wendt, and Jeffrey Aubé, Organic Letters, 2002, 4, 2577-2579.
67. "Asymmetric Total Synthesis of Dendrobatid Alkaloid 251F." Aaron Wrobleski, Kiran Sahasrabudhe, and Jeffrey Aubé, Journal of the American Chemical Society, 2002, 124, 9974-9975.
68. "Ring Expansive Routes to Quinolizidine Alkaloids: Formal Synthesis of (–)-Lasubine II." Vijaya Gracias, Yibin Zeng, Pankaj Desai, and Jeffrey Aubé, Organic Letters, 2003, 5, 4999-5001.
69. "Unusual Tethering Effects in the Schmidt Reaction of Hydroxyalkyl Azides with Ketones: Cation- and Steric Stabilization of a Pseudoaxial Phenyl Group." Christopher E. Katz and Jeffrey Aubé, Journal of the American Chemical Society, 2003, 125, 13948-13949.
70. "Lewis Acid-Mediated Reactions of Alkyl Azides with a,ß-Unsaturated Ketones." D. Srinivasa Reddy, Weston R. Judd, and Jeffrey Aubé, Organic Letters, 2003, 5, 3899-3902.
71. "Asymmetric Schmidt Reaction of Hydroxyalkyl Azides with Ketones." Kiran Sahasrabudhe, Vijaya Gracias, Kelly Furness, Brenton T. Smith, Christopher E. Katz, D. Srinivasa Reddy, and Jeffrey Aubé, Journal of the American Chemical Society, 2003, 125, 7914-7922.
72. "Rearrangements of Bicyclic Nitrones to Lactams: Comparison of Photochemical and Modified Barton Conditions." Yibin Zeng, Brenton T. Smith, John Hershberger, and Jeffrey Aubé, Journal of Organic Chemistry, 2003, 68, 8065-8067.
73. "Ab Initio Approach to Understanding the Stereoselectivity of Reactions between Hydroxyalkyl Azides and Ketones." N. Deborah Hewlett, Jeffrey Aubé, and Jennifer L. Radkiewicz-Poutsma, Journal of Organic Chemistry, 2004, 69, 3439-3446.
74. "Synthesis and Conformational Studies of Dipeptides Constrained by Disubstituted 3-(Aminoethoxy)propionic Acid Linkers." D. Srinivasa Reddy, David Vander Velde, and Jeffrey Aubé, Journal of Organic Chemistry, 2004, 69, 1716-1719.
75. "Asymmetric Total Synthesis of Dendrobatid Alkaloids: Preparation of Indolizidine 251F and Its 3-Desmethyl Analogue Using an Intramolecular Schmidt Reaction Strategy." Aaron Wrobleski, Kiran Sahasrabudhe, and Jeffrey Aubé, Journal of the American Chemical Society, 2004, 126, 5475-5481.
76. "Base-Promoted Reactions of Bridged Ketones and 1,3- and 1,4-Haloalkyl Azides: Competitive Alkylation vs Azidation Reactions of Ketone Enolates." Lei Yao, Brenton T. Smith, and Jeffrey Aubé, Journal of Organic Chemistry, 2004, 69, 1720-1722.
77. "Domino Reactions That Combine an Azido-Schmidt Ring Expansion with the Diels-Alder Reaction.” Yibin Zeng, D. Srinivasa Reddy, Erin Hirt, and Jeffrey Aubé, Organic Letters, 2004, 6, 4993-4995.
78. "Modular Synthesis of Cyclic Peptidomimetics Inspired by g-Turns.” Senthil Kumar Ramanathan, John Keeler, Huey-Lih Lee, D. Srinavasa Reddy, Gerald Lushington, and Jeffrey Aubé, Organic Letters, 2005, 7, 1059-1062.
79. “Facile C-N Cleavage in a Series of Bridged Lactams.” Yao Lei, Aaron D. Wrobleski, Jennifer E. Golden, Douglas R. Powell, and Jeffrey Aubé, Journal of the American Chemical Society, 2005, 127, 4552-4553.
80. “Synthesis of a Small Library of Diketopiperazines as Potential Inhibitors of Calpain.” Yibin Zeng, Qingshan Li, Robert P. Hanzlik, and Jeffrey Aubé, Bioorganic and Medicinal Chemistry Letters, 2005, 15, 3034-3038.
81. “Regioselective Single and Double Conjugate Additions to Substituted Cyclohexa-2,5-Dienone Monoacetals.” Scott Grecian, Aaron D. Wrobleski, and Jeffrey Aubé, Organic Letters, 2005,7, 3167-3170.
82. “An Expeditious Total Synthesis of (±)-Stenine.” Yibin Zeng and Jeffrey Aubé, Journal of the American Chemical Society, 2005, 127, 15712–15713.
83. “Revisiting a Classic Approach to the Aspidosperma Alkaloids: An Intramolecular Schmidt Reaction-Mediated Synthesis of (+)-Aspidospermidine.” Rajesh Iyengar, Klaas Schildknegt, Martha Morton, and Jeffrey Aubé, Journal of Organic Chemistry, 2005, 70, 10645-10662.
84. “Cyclization of a Carbon-Centered Radical Derived from Oxaziridine Cleavage.” Yoshinosuke Usuki, Xin Peng, Belgin Gülgeze, and Jeffrey Aubé, Arkivoc, 2006, part iv, 189–199. Special issue in honor of Professor Armand Lattes.
85. “Remote Control of Diastereoselectivity in Intramolecular Reactions of Chiral Allylsilanes.” Weston R. Judd, Sooho Ban, and Jeffrey Aubé, Journal of the American Chemical Society, 2006, 128, 13736–13741.
86. “Solution-Phase Parallel Synthesis of a Library of 2-Pyrazolines.” Shankar Manyem, Mukund P. Sibi, Gerald H. Lushington, Benjamin Neuenswander, Frank Schoenen, and Jeffrey Aubé, Journal of Combinatorial Chemistry, 2007, 9, 20–28.
87. “Cation–p Control of Regiochemistry of Intramolecular Schmidt Reactions en Route to Bridged Bicyclic Lactams.” Lei Yao and Jeffrey Aubé, Journal of the American Chemical Society, 2007, 129, 2766–2767.
88. “One-Step Synthesis of Oxazoline and Dihydrooxazine Libraries.” Priyanka Chaudhry, Frank Schoenen, Benjamin Neuenswander, Gerald H. Lushington, and Jeffrey Aubé, Journal of Combinatorial Chemistry, 2007, 9, 473–476.
89. “Intramolecular and Intermolecular Schmidt Reactions of Alkyl Azides with Aldehydes.” Huey-Lih Lee and Jeffrey Aubé, Tetrahedron, 2007, 63, 9007–9015.
90. “Synthesis of an N-Substituted Lactam Using an Intramolecular Schmidt Reaction.” Scott Grecian and Jeffrey Aubé, Organic Syntheses, 2007, 84, 347–358. Procedure checked by Dalian Zhao and David J. Mahre.
91. “Double Conjugate Addition of a Nitropropionate Ester to a Quinone Monoketal: Synthesis of an Advanced Intermediate to (±)-Gelsemine.” Scott Grecian and Jeffrey Aubé, Organic Letters, 2007, 9, 3153–3156.
92. “Synthesis of Isoquinol-1-one-8-carboxylic Acid Libraries Using a Tandem Diels–Alder/Acylation Sequence.” Kevin J. Frankowski, Erin E. Hirt, Yibin Zeng, Ben Neuenswander, Drew Fowler, Frank Schoenen, and Jeffrey Aubé, Journal of Combinatorial Chemistry, 2007, 9, 1188–1192.
93. “Reactions of Cyclopropanone Acetals with Alkyl Azides: Carbonyl Addition versus Ring-Opening Pathways.” Scott Grecian, Pankaj Desai, Craig Mossman, Jennifer L. Poutsma, and Jeffrey Aubé, Journal of Organic Chemistry, 2007, 72, 9439–9447.
94. “Nucleophilic Addition to Iminium Ethers in the Preparation of Functionalized N-Alkyl Heterocycles.” Erik Fenster, Brenton T. Smith, Vijaya Gracias, Gregory L. Milligan, and Jeffrey Aubé, Journal of Organic Chemistry, 2008, 73, 201–205.
95. “Synthesis of Enantiomerically Enriched (R)-5-tert-Butylazepan-2-one Using a Hydroxyalkyl-azide Mediated Ring Expansion Reaction.” Timothy P. Ribelin and Jeffrey Aubé, Nature: Protocols, 2008, 3, 137–143.
96. “Three-Component Synthesis of 1,4-Diazepin-5-ones and the Construction of γ Turn-like Peptidomimetic Libraries.” Erik Fenster, Dinesh K. Rayabarapu, Mianji Zhang, Shubhasish Mukherjee, David Hill, Ben Neuenswander, Frank Schoenen, Paul R. Hanson, and Jeffrey Aubé, Journal of Combinatorial Chemistry, 2008, 10, 230–234.
97. “Efficient Synthesis of γ-Lactams by a Tandem Reductive Amination/Lactamization Sequence.” Julica Nöth, Kevin J. Frankowski, Benjamin Neuenswander, Jeffrey Aubé, and Oliver Reiser, Journal of Combinatorial Chemistry, 2008, 10, 456–459.
98. “Syntheses of the Stemona Alkaloids (±)-Stenine, (±)-Neostenine, and (±)-13-Epineostenine Using a Stereodivergent Diels–Alder/Azido-Schmidt Reaction.” Kevin J. Frankowski, Jennifer E. Golden, Yibin Zeng, Yao Lei, and Jeffrey Aubé, Journal of the American Chemical Society, 2008, 130, 6018–6024.
99. “Non-Bonded, Attractive Cation–π Interactions in Azide-Mediated Asymmetric Ring Expansion Reactions.” Christopher E. Katz, Timothy Ribelin, Donna Withrow, Yashar Basseri, Anna K. Manukyan, Amy Bermudez, Christian G. Nuera, Victor W. Day, Douglas R. Powell, Jennifer L. Poutsma, and Jeffrey Aubé, Journal of Organic Chemistry, 2008, 73, 3318 - 3327. Selected by the editor as a Feature Article.
100. “Highly Stereoselective Ring Expansion Reactions Mediated by Attractive, Non-Bonded Cation–n Interactions.” Timothy Ribelin, Christopher E. Katz, Donna Withrow, Sherriel Smith, Anna Manukyan, Victor W. Day, Benjamin Neuenswander, Jennifer L. Poutsma, and Jeffrey Aubé, Angewandte Chemie, International Edition, 2008, accepted.
101. “Explorations of Stemona Alkaloid-Inspired Analogues: Skeletal Modification and Functional Group Diversification.” Kevin J. Frankowski, Benjamin Neuenswander, and Jeffrey Aubé, Journal of Combinatorial Chemistry, 2008, 10, accepted.
Books, Book Chapters, and Review Articles (To Top of Page)
1. "Epoxidation and Related Processes." Jeffrey Aubé, In Comprehensive Organic Synthesis; B.M. Trost and I. Fleming, Eds.; Pergamon Press: Oxford, 1991; Vol. 1, pp. 819-842.
2. "N-(tert-Butoxycarbonyloxy)phthalimide." Michael S. Wolfe and Jeffrey Aubé, In Encyclopedia of Reagents for Organic Synthesis; L.A. Paquette, Ed.; John Wiley and Sons: Sussex, 1995; Volume 2, pp. 838-839.
3. "Asymmetric Approaches to the Yohimbine Alkaloids: Development of a Group-Selective Ring-Expansion Process and Its Application to Total Synthesis." Jeffrey Aubé and Shomir Ghosh, In Advances in Heterocyclic Natural Products Synthesis; W.H. Pearson, Ed.; JAI Press: Greenwich, Connecticut, 1996; Vol. 3, pp. 99-150.
4. Principles of Asymmetric Synthesis. Robert E. Gawley and Jeffrey Aubé, Tetrahedron Organic Chemistry Series; J.E. Baldwin, Series Editor; Pergamon Press: Oxford, 1996; Volume 14, 372 pp.
5. "Asymmetric Synthesis." Jeffrey Aubé, In Encyclopedia of Chemistry; J.J. Lagowski, Ed.; Volume 1; Macmillan Reference USA, Simon & Schuster Macmillan: New York, 1997; Volume 1, pp. 176-179.
6. "Synthesis of LactamPeptidomimetics." Jeffrey Aubé, In Advances in Amino Acid Mimetics andPeptidomimetics; A. Abell, Ed.; JAI Press: Greenwich, Connecticut, 1997; Vol. 1, pp. 93-232.
7. "Improvement of Oral Peptide Bioavailability: Peptidomimetic and Prodrug Strategies." Giovanni M. Pauletti, Sankeev Gangwar, Teruna J. Siaahan, Jeffrey Aubé, and Ronald T. Borchardt, Advanced Drug Delivery Reviews, 1997, 27, 235-256.
8. "Oxaziridine Rearrangements in Asymmetric Synthesis." Jeffrey Aubé, Chemical Society Reviews, 1997, 26, 269-277.
9. "Approaches to Cyclic Β -Turn Mimetics." Mary MacDonald and Jeffrey Aubé, Current Organic Chemistry, 2001, 5, 89-111.
10. “Amides and Derivatives; Polyamides and Peptides: Lactams. 21.1.5. Product Subclass 1: Synthesis by Rearrangement.” In Science of Synthesis, Vol. 22: Three-Carbon Heteroatom Bonds: Amides and Derivatives, Peptides, Lactams. Ed. Weinreb, S. Weston Judd, Christopher E. Katz, and Jeffrey Aubé, George Thieme verlag KG: Stuttgart, 2005, 133–178.
11. “The Total Synthesis of Amphibian Alkaloids Using the Intramolecular Schmidt Reaction.” Kevin J. Frankowski, Aaron Wrobleski and Jeffrey Aubé, In Strategies and Tactics in Organic Synthesis, Vol. 7, Elsevier: Amsterdam, 2008, 408–459.
Miscellaneous Publications, Short Reviews, Book Reviews, and Other Scholarly Work (To Top of Page)
1. "Synthesis of Optically Active 3-Oxacarbacyclin Precursors Featuring Asymmetric Horner-Emmons Reaction." Jeffrey Aubé, Chemtracts – Organic Chemistry, 1988, 1, 461-464.
2. "New C2-Symmetrical Chiral Secondary Amines." Jeffrey Aubé, Chemtracts – Organic Chemistry, 1989, 2, 46-49.
3. "Peptide Architecture: Design of Stabilized a-Helical Metalloproteins." Jeffrey Aubé, Chemtracts – Organic Chemistry, 1991, 4, 135-139.
4. "The Synthesis and Some Properties of the First Boron-Stabilized Alkenyl Carbanions.” Jeffrey Aubé, Chemtracts – Organic Chemistry, 1992, 5, 374-375.
5. "Asymmetric Synthesis of Organometallic Complexes with Planar Chirality Using Diastereotopic Group-Selective Reactions." Jeffrey Aubé, Chemtracts – Organic Chemistry, 1994, 7, 52-56.
6. "Chiral Base-Mediated Asymmetric Synthesis of Tricarbonyl(?6-Arene) Chromium Complexes. Planar Chiral Arene Tricarbonylchromium Complexes via Enantioselective Deprotonation/Electrophile Addition Reactions." Jeffrey Aubé and John A. Wendt, Chemtracts – Organic Chemistry, 1994, 7, 413-414.
7. "Synthetic Applications of Dispiroketals." Michael Z. Hoemann and Jeffrey Aubé, Chemtracts – Organic Chemistry, 1995, 8, 26-35.
8. "Synthesis of Conformationally Restricted Amino Acids and Peptides Employing Olefin Metathesis." Vijaya Gracias and Jeffrey Aubé, Chemtracts – Organic Chemistry, 1995, 8, 363-367.
9. Book review of "Studies in Natural Products Chemistry: Vol. 16, Stereoselective Synthesis (Part J)" (A.-u. Raman, Ed.; Elsevier: The Netherlands, 1995). Jeffrey Aubé, Journal of the American Chemical Society, 1996, 118, 4918.
10. "Ionic Diels-Alder Chemistry: Contemporary Interpretations of the Gassman Reaction." Klaas Schildknegt and Jeffrey Aubé, Chemtracts – Organic Chemistry, 1996, 9, 237-241.
11. "The -Arene Chromium Complex as a Facial Selectivity Control Element: the Enantioselective Synthesis of Cetirizine Hydrochloride." Klaas Schildknegt and Jeffrey Aubé, Chemtracts – Organic Chemistry, 1997, 10, 1-4.
12. “A Decade of Combining Teaching and Research.” Jeffrey Aubé, In Reflections from the Classroom; Fred Rodriguez and Judy Eddy, Eds.; Center for Teaching Excellence, University of Kansas: Lawrence, KS, 1998; pp 14-17.
13. Book review of “Metal-catalyzed Cross-coupling Reactions” (François Diederich and Peter J. Stang, Eds.; Wiley–VCH: Weinheim, 1998). Jeffrey Aubé, Journal of Medicinal Chemistry, 1999, 42, 1112.
14. “The Family Approach to the Resolution of Racemates.” Kiran Sahasrabudhe and Jeffrey Aubé, Chemtracts – Organic Chemistry, 1999, 12, 672-674.
15. “The First Total Synthesis of (–)-FR901483.” Jennifer E. Forsee and Jeffrey Aubé, Chemtracts – Organic Chemistry, 1999, 12, 1026-1031.
16. “Oxaziridines as N- and O-Functionalization Reagents.” Rajesh Iyengar and Jeffrey Aubé, Chemtracts – Organic Chemistry, 2000, 13, 36-41.
17. “New Advances in Peptidomimetics and Peptides (Preface).” Jeffrey Aubé, Tetrahedron, 2000, 56, ix.
18. Book review of "Principles and Applications of Asymmetric Synthesis” (Guo-Qiang Lin, Yue-Ming Li, and Albert S.C. Chan; Wiley Interscience: New York, 2001). Jeffrey Aubé, Journal of Medicinal Chemistry, 2001, 44, 4741.
19. Reflections from the Classroom, Judith Eddy and Jeffrey Aubé, Eds., Center for Teaching Excellence, University of Kansas: Lawrence, KS, 2002. Co-edited volume and contributed Foreword.
20. “Five Years Into the Future: Reflections on the Center for Teaching Excellence”, Jeffrey Aubé, Judith Eddy, and Sandra Gautt. In Reflections from the Classroom, Judith Eddy and Jeffrey Aubé, Eds., Center for Teaching Excellence, University of Kansas: Lawrence, KS, 2002, 5, 1-3.
21. "Total Syntheses of Martinella Alkaloids." Weston R. Judd and Jeffrey Aubé, Chemtracts – Organic Chemistry, 2003, 16, 105-116.
22. "Arthur Suite V. 3.0 Symyx Technologies, Inc.” Software review. Frank Schoenen and Jeffrey Aubé, Journal of the American Chemical Society, 2006, 128, 664–665.
23. “Paying the Pipeliner: Academic Investment in Early Stage Drug Discovery”, Jeffrey Aubé. In The Privatization of Public Universities: Implications for the Research Mission, Mabel L. Rice and Sally Hayden, Eds., Merrill Advanced Studies Center, University of Kansas: Lawrence, KS, 2006, pp 23-33. Available online at
http://merrill.ku.edu/publications/2006whitepaper.pdf.
24. Short commentary on “The Catalytic Cross-coupling of Unactivated Arenes” by D. R. Stuart and K. Fagnou, Science 2007, 316, 1172–1175. June 21, 2007. Available online at
http://www.f1000biology.com/article/id/1087318/evaluation.
25. Short commentary on “Epoxide-opening Cascades Promoted by Water” by I. Vilotijevic and T.F. Jamison, Science 2007 317, 1189-1192. October 24, 2007. Available online at
http://www.f1000biology.com/article/id/1089741/evaluation.
26. Short commentary on “Diastereoselective Synthesis of γ-Lactams by a One-Pot, Four-Component Reaction” by Jingqiang Wei and Jared T. Shaw, Organic Reactions, 2007, 9, 4077-4081. Available online at
http://www.f1000biology.com/article/id/1098143/evaluation.
27. Short commentary on “Preparative Scale Baeyer-Villiger Biooxidation at High Concentration Using Recombinant Escherichia Coli and In Situ Substrate Feeding and Product Removal Process” by I. Hilker, M. C. Gutiérrez, R. Furstoss, J. Ward, R. Wohlgemuth, and V. Alphand, Nature: Protocols, 2008, 3, 546–554. Available online at
http://www.f1000biology.com/article/id/1104505/evaluation.
