1. SA David, VI Mathan & P Balaram. “Interaction of melittin with endotoxic lipid A.“ Biochim. Biophys. Acta 1123 (1992): 269-274.
2. SA David, KA Balasubramanian, VI Mathan & P Balaram. “Analysis of the binding of polymyxin B to endotoxic lipid A and core glycolipid using a fluorescent displacement probe.” Biochim. Biophys. Acta. 1165 (1992): 147-152.
3. SA David, P Balaram & VI Mathan. “Interaction of basic amphiphilic polypeptide antimicrobials, Gramicidin S, Tyrocidin, and Efrapeptin, with endotoxic lipid A. Med.” Med. Microbiol. Lett. 2 (1993): 42-47.
4. SA David & VI Mathan. “Enzyme-linked immunosorbent assay for quantification of anti-lipid A antibody. Enhancement of sensitivity by antigen immobilization at low pH.” J. Immunol. Methods 163 (1993): 85-89.
5. R Koshi, VI Mathan, SA David & MM Mathan. “Enteric vascular endothelial response to bacterial endotoxin.” Int. J. Exp. Path. 74 (1993): 593-601.
6. SA David, B Bechtel, C. Annaiah, VI Mathan & P Balaram. “Interaction of cationic amphiphilic drugs with lipid A: Implications for development of endotoxin antagonists.” Biochim. Biophys. Acta. 1212 (1994): 167-175.
7. SA David, P Balaram & VI Mathan. “Characterization of the interaction of lipid A and lipopolysaccharide with human serum albumin: Implications for an endotoxin carrier function for albumin.” J. Endotoxin Res. 2 (1995): 99-106.
8. SA David, VI Mathan & P Balaram. “Interactions of linear dicationic molecules with lipid A: Structural features that correspond to optimal binding affinity.” J. Endotoxin Res. 2 (1995): 325-336.
9. SA David, SK Awasthi, A Wiese, AJ Ulmer, B Lindner, K Brandenburg, U Seydel, ETh Rietschel, A Sonesson & P Balaram. “Characterization of the interactions of a polycationic, amphiphilic, terminally-branched oligopeptide with lipid A and lipopolysaccharide from the deep rough mutant of Salmonella minnesota.” J. Endotoxin Res. 3 (1996): 369-379.
10. S Bhattacharjya, SA David, VI Mathan & P Balaram. “Polymyxin B nonapeptide: Conformations in water and in the lipopolysaccharide-bound state determined by 2D-NMR and molecular dynamics.” Biopolymers 41 (1997): 251-265.
11. SA David, R Silverstein, C Amura, T Kielian & DC Morrison. “Lipopolyamines: Novel antiendotoxin compounds that reduce mortality in experimental sepsis.” Antimicrob. Agents Chemother. 43 (1999): 912-919.
12. SA David, SK Awasthi, P Balaram. “The Role Of Polar And Facial Amphipathic Character In Determining Lipopolysaccharide-Binding Properties In Synthetic Cationic Peptides.” J. Endotoxin Res. 6 (2000): 249-56.
13. IS Blagbrough, AJ Geall, SA David. “Lipopolyamines incorporating the tetraamine spermine, bound to an alkyl chain, sequester bacterial lipopolysaccharide.” Bioorg. Med. Chem. Lett. 10 (2000): 1959-62.
14. SA David, L Pérez M.-R. Infante. “Sequestration of bacterial lipopolysaccharide by bis(args) gemini compounds.” Bioorg. Med. Chem. Lett. 12 (2002): 357-360.
15. Towards a rational development of anti-endotoxin agents: novel approaches to sequestration of bacterial endotoxins with small molecules. J. Molec. Recognition 14 (2001): 370-387.
16. SJ Wood, KA Miller, and SA David. “Anti-Endotoxin Agents. 1. Development of a Fluorescent Probe Displacement Method Optimized for the Rapid Identification of Lipopolysaccharide-Binding Agents.” Combi. Chem. High Throughput Screen. 2004. In Press.
17. SJ Wood, KA Miller, and SA David. “Anti-Endotoxin Agents. 2. Pilot High-Throughput Screening for Novel Lipopolysaccharide-Recognizing Motifs in Small Molecules.” Combi. Chem. High Throughput Screen. 2004. In Press.
For More Information, Please Contact:
Dr. Sunil A. David
KU Life Sciences Research Laboratories
1501 Wakarusa Drive
Lawrence, KS 66049
Email:
sdavid@ku.edu
Tel: +785-330-4316
Fax: +785-330-4332
