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Barbara N. Timmermann - Publications

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Selected Publications (from over 180)


Books (from 9)


Books (co-authored)


Yoshioka, H., T.J. Mabry and B.N. Timmermann. "Sesquiterpene Lactones, Nuclear Magnetic Resonance, Chemistry and Distribution." The University of Tokyo Press, Tokyo, 1972, 544 pp.

Montenegro, G. and B.N. Timmermann. "Chile, Nuestra Flora Util. Especies de uso Apicola, Alimentario en Medicina Folclorica, Artesanal y Ornamental". Abaco Press, Santiago, Chile, 2000, 284 pp.

Books (co-edited)


Timmermann, B.N., C. Steelink and F.A. Loewus. "Recent Advances in Phytochemistry," Vol. 18. "Phytochemical Adaptations to Stress." Plenum Press, New York, 1984, 334 pp.

Whitehead, E.E., C.F. Hutchinson, B.N. Timmermann and R.G. Varady. 1987. "Arid Lands: Today and Tomorrow." Proceedings of an International Research and Development Conference. October 20-25, 1985. Westview Press, Boulder, Colorado. 1435 pp.

Chapters (from 18)


Timmermann, B.N. “Biodiversity Prospecting in Drylands of Latin America” in “Combating Desertification with Plants”, D. Pasternak and A. Schliessel (Eds.), pp 97-111, Kluwer Academic/Plenum Publishers, NY (2001).

Montenegro, G., Gomez, M.,Mujica, A.M., and Timmermann B.N. "Theoretical Models for Regeneration of Medicinal Plants and Their Application in Sustainable Wild Harvesting. Pp 275-290 in: Lemons, J., R. Victor, and D. Schaffer (eds.), Conserving Biodiversity in Drylands: Best Practices in Developing Nations. Kluwer Academic Publishers, Norwell, MA 513 pgs. (2003).

Pfeiffer, E., H. Esch, S. Hohle, A. Solyom, B.N. Timmermann and M. Metzler.“ In vitro studies on the estrogenic activity and the metabolism of curcumin. In: Functional Foods: Safety Aspects (G. Eisenbrand, Ed). Deutsche Forschungsgemeinschaft, Senate Commission on Food Safety, Wiley-VCH Verlag, Weinheim, pp. 325-329 (2003).

Timmermann, B.N. “Chemistry and Mechanisms of Action of Anti-Inflammatory Botanicals“. Pp.95-102 in: Proceedings from the Eighth Shizuoka Forum on Health and Longevity, Biomedical and Sociological Approaches toward a Healthy Longevity-Society, Shizuoka, Japan, 175 pgs. (2004)

Timmermann, B.N. 2005. Biodiversity Prospecting in Drylands of Latin America. In Biodiversity & Health: Focusing Research to Policy. Proceedings of the International Symposium, held in Ottawa, Canada, October 25–28. Edited by J.T. Arnason, P.M. Catling, E. Small, P.T. Dang, and J.D.H. Lambert. NRC Research Press, Ottawa, Ontario. pp. 79–84. (2003).

Peer-reviewed Publications (selected from a total of ca. 150 publications, over 40 in the last four years)


Valcic, S., B.N.Timmermann, D.S. Alberts, G.A. Wächter, M. Krutzsch, J. Wymer and J. Guillen. 1996. Inhibitory Effect of Six Green Tea Catechins and Caffeine on the Growth of Four Selected Human Tumor Cell Lines. Anti Cancer Drugs 7: 461-468.

Gensler, H., B.N. Timmermann, S. Valcic and G. Wächter. 1996. Prevention of Photo-carcinogenesis by Topical Administration of Pure Epigallocatechin Gallate Isolated from Green Tea. Nutrition and Cancer 26(3): 325-335.

Barthelman, M., W.B. Bair III, K.K. Stickland, W. Chen, B.N. Timmermann, S. Valcic, Z. Dong and G.T. Bowden. 1998. (-)-Epigallocatechin-3-gallate inhibition of ultraviolet B-induced AP-1 activity. Carcinogenesis. 19(12): 2201-2204.

Chen, W., Z. Dong, S. Valcic, B.N. Timmermann and G.T. Bowden. 1999. Inhibition of Ultraviolet B-induced c-fos Gene Expression and p38 Mitogen-Activated Protein Kinase Activation by (-)-Epigallocatechin Gallate in a Human Keratinocyte Cell Line. Molecular Carcinogenesis 24(2): 79-84.

Dvorakova, K., R.T. Dorr, S. Valcic, B.N.Timmermann and D.S. Alberts. 1999. Pharmacokinetics of the green tea derivative, EGCG, by the topical route of administration in mouse and human skin. Cancer Chemotherapy and Pharmacology 43: 331-335.

Valcic, S., A. Muders, N.E. Jacobsen, D.L. Liebler, and B.N. Timmermann. 1999. Antioxidant chemistry of green tea catechins. Identification of products of EGCG reaction with peroxyl radicals. Chem. Res. in Toxicol. 12(4): 382 386.

Waechter, G., S. Valcic, M.L. Flagg, S.G. Franzblau, G. Montenegro, E. Suarez and B.N. Timmermann. 1999. Antitubercular activity of pentacyclic triterpenoids from plants of Argentina and Chile. Phytomedicine 6(5): 341-345.

Valcic, S., J.A. Burr, B.N. Timmermann and D.C. Liebler. 2000. Antioxidant Chemistry of Green Tea Catechins. New oxidation products of (-)- epigallocatechin gallate and (-)- epigallocatechin from their reactions with peroxyl radicals. Chem. Res. Toxicol.13(A): 801-810.

Timmermann, B.N., G. Wachter, S. Valcic, B. Hutchinson, J. Henzel, C. Casler, S. Ram, F. Currim, R. Manak, S. Franzblau, W. Maiese, D. Galinis, E. Suarez, R. Fortunato, E. Saavedra, R. Bye, R. Mata and G. Montenegro. 1999.The Latin American ICBG: The First Five Years. Pharm. Biol. 37, Supplement, 35-54.

Gezginci, M.H. and B.N. Timmermann. 2001. A short synthetic route to nordihydroguaiaretic acid (NDGA) and its stereoisomer using Ti-induced carbonyl-coupling reaction.Tetrahedron Letters 42: 6083-6085.

Wachter, G., S.G. Franzblau, G. Montenegro, J.J. Hoffmann, W.M. Maiese and B.N. Timmermann. 2001. Inhibition of Mycobacterium tuberculosis growth by saringosterol from Lessonia nigrescens. J. Nat. Prod. 64 (11): 1463-1464.

Whitman, S., M. Gezginci, B.N. Timmermann & T.R. Holman. 2002. Structure-Activity Relationship Studies of Nordihydroguaiaretic Acid Inhibitors toward Soybean, 12-Human, and 15-Human Lipoxygenase. J. Med. Chem. 45(12), 2659-2661.

Lambert, J.D., D. Zhao, R.O. Meyers, R.K. Kuester, B.N. Timmermann and R.T. Dorr. 2002. Nordihydroguaiaretic acid: hepatotoxicity and detoxification in the mouse. Toxicon 40: 1701-1708.

Jolad, S., L.C. Lantz, A. M. Solyom, G.J. Chen, R.B. Bates, and B.N. Timmermann. 2004. “Fresh organically grown ginger (Zingiber officinale): composition and effects on LPS-induced PGE2 production Phytochemistry 65:1937-1954.

Lambert, J.D., Dorr, R.T., and Timmermann, B.N. 2004. "Nordihydroguaiaretic Acid: A Review of its Numerous and Varied Biological Activities." Pharmaceutical Biology. 42(2): 149-158.

Khera, S., Carducci, M., Michael, D., Gu, J Q., and Timmermann, B.N. 2004. "(4R,5R,7S,8S,9S) 7 hydroxy 8 hydroxymethyl 4 methyl perhydrocyclopenta[c]pyran 1 one from Valeriana laxiflora". Acta Cryst.C60, o773 o775.

Kiela, P.R., Midura, A.J., Kuscuoglu, N., Jolad, S.D., Solyom, A.M., Besselsen, D.G., Timmermann, B.N., and Ghishan, F.K. 2004. “Boswellia serrata does not offer protection and is potentially hepatotoxic in mouse models of chemically induced colitis”. Am J Physiol Gastrointest Liver Physiol, Nov 2004; 10.1152/ajpgi.00433.2004.

Mata, R., Morales, I., Perez, O., Rivero-Cruz, I., Acevedo, L., Enriquez-Mendoza, I., Bye, R., Franzblau, S.G., and Timmermann, B.N. 2004. “Antimicrobacterial Compounds from Piper sanctum”. J. Nat Prod 67(12): 1961-1968.

Gu, J-Q., Wang, Y., Franzblau, S., and Timmermann, B.N. 2004. "Constituents of Quinchamalium majus with Potential Antitubercular Activity”. Z. Naturforsch 59(c), 797-802.

Lambert, J.D., Sang, S., Dougherty, A., Caldwell, C.G., Meyers, R.O., Dorr, R.T., and Timmermann, B.N. 2005. Cytotoxic lignans from Larrea tridentate. Phytochemistry 66(7), 811-815.

Jolad, S.D., Lantz, R.C., Solyom, A.M., Chen, C.J., Bates, R.B. and Timmermann, B.N. 2005.Commercially processed dry ginger (Zingiber officinale): Composition and effects on LPS-induced PGE2 prouction. Phytochemistry 66(13), 1614-1635.

Jiang, H., A. Solyom, B. N. Timmermann, D. Gang. 2005. Characterization of gingerol-related compounds in ginger rhizome (Zingiber officinale Rosc.) by high performance liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun.Mass Spectrom. 19, 2957-2964.

Gutierrez-Lugo, M.T., Y. Wang, S. G. Franzblau, E. Suarez and B. N. Timmermann. 2005. Antitubercular sterols from Thalia multiflora Horkel ex Koernicke. Phytother. Res. 19, 876-880.

Jiang, H., B. N. Timmermann and D. R. Gang. 2006. Use of liquid chromatography-electrospray ionization tandem mass spectrometry to identify diarylheptanoids in turmeric (Curcuma longa L.) rhizome. J Chromat. A 1111, 21-31.

Jiang, H., A. Somogyi, N.E. Jacobsen, B.N. Timmermann and D.R. Gang. 2006. Analysis of curcuminoids by positive and negative elctrospray ionization and tandem mass spectrometry. 2006. Rapid Comm. Mass. Spectrom. 20, 1001-1012.

Johnson, L., H. Strich, A. Taylor, B. Timmermann, D. Malone, N. Teufel-Shone, R. Drummond, R. Woosley, E. Pereira and A. Martinez. 2006. Phytother. Res. 20, 250-255.

For More Information, Please Contact:



Dr. Barbara N. Timmermann
University Distinguished Professor and Chair
Department of Medicinal Chemistry
1251 Wescoe Hall Dr.
4070 Malott Hall
Tel: 785-864-4844
FAX: 785-864-5326
Email: btimmer@ku.edu